Involvement of ion channels and transporters in carcinoma angiogenesis
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چکیده
3 Author: Sonia MARTIAL 4 5 Affiliation: 6 IRCAN, CNRS UMR 7284, Inserm U1081, Université Nice-Sophia Antipolis, NICE, FRANCE 7 8 Running title: Ion transport modulates tumor angiogenesis and metastasis 9 10 Corresponding author: 11 Dr. Sonia MARTIAL 12 CNRS UMR 7284 – INSERM U 1081 – UNS 13 Institute for Research on Cancer and Aging, Nice 14 33 avenue Valombrose 15 06189 NICE CEDEX 2 16 FRANCE 17 e-mail : [email protected] 18 Tel : +33 4 92 03 12 27 / +33 4 92 03 12 28 19 Fax : +33 4 92 03 12 35 20 21 Articles in PresS. Am J Physiol Cell Physiol (January 20, 2016). doi:10.1152/ajpcell.00218.2015
منابع مشابه
Involvement of ion channels and transporters in carcinoma angiogenesis and metastasis.
Angiogenesis is a finely tuned process, which is the result of the equilibrium between pro- and antiangiogenic factors. In solid tumor angiogenesis, the balance is highly in favor of the production of new, but poorly functional blood vessels, initially intended to provide growing tumors with nutrients and oxygen. Among the numerous proteins involved in tumor development, several types of ion ch...
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Ion channels are naturally occurring pores through the proteins that regulate the passage of ions and thus maintain the concentration of ions inside and outside the cell. The ion channels control many physiological functions and they can show selectivity for a specific ion. Ion channels are mostly observed in nerve cells and muscle cells. The influx of ions into cells can be regulated by a gate...
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تاریخ انتشار 2016